Electrical Status Epilepticus in Sleep: Clinical Presentation and Pathophysiology
نویسندگان
چکیده
منابع مشابه
Pathophysiology of Status Epilepticus
Status epilepticus is refractory to initial intravenous anticonvulsants in every third patient and at least the generalised convulsive form is commonly associated with neuronal long-term consequences. The understanding of pathophysiological mechanisms underlying development and maintenance of status epilepticus and its sequelae is therefore of uttermost importance. Spontaneous seizure terminati...
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As in Clark and Prout's classic work, we identify three phases of generalised convulsive status epilepticus, which we call impending, established, and subtle. We review physiological and subcellular changes that might play a part in the transition from single seizures to status epilepticus and in the development of time-dependent pharmacoresistance. We review the principles underlying the treat...
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We describe two individuals with the same chromosomal aberrations derived from an unbalanced translocation between chromosomes 8p and 9p, who presented with intellectual disabilities, dysmorphic features, and localization-related epilepsy. Several years after the onset of epilepsy, aggravation of widespread epileptic discharges during sleep resulted in the emergence of absence and/or atonic sei...
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Encephalopathy with status epilepticus during sleep (ESES) is an epileptic encephalopathy, as defined by the International League Against Epilepsy (ILAE) Task Force on Classification and Terminology, that is, a condition in which the epileptic processes themselves are believed to contribute to the disturbance in cerebral function. Clinical manifestations of ESES are heterogeneous: apart from di...
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ژورنال
عنوان ژورنال: Pediatric Neurology
سال: 2012
ISSN: 0887-8994
DOI: 10.1016/j.pediatrneurol.2012.06.016